Comprehensive Review on Drug-Loaded Niosomes: A Promising Nanocarrier-based System

Vesicular drug delivery systems, niosomes are currently innovative delivery systems that encapsulate hydrophilic and hydrophobic drugs into the core and the bilayer of these niosomes. Niosomes are composed of non-ionic surfactants and differ from traditional liposomes by having chemical stability and smaller drug leakage. Targeted drug delivery with enhanced therapeutic efficiency is achieved, as well as a reduction in side effects and increased drug presence at the target site. Preparation of niosomes, their types, advantages and drawbacks are discussed in this review.